Ototoxic medications are those that can damage the ear and cause hearing loss or balance problems. Some common ototoxic medications include:
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Aspirin (in high doses)
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Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen
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Certain antibiotics, including aminoglycosides (such as gentamicin) and vancomycin
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Cancer chemotherapy agents such as cisplatin
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Some diuretics, including furosemide (Lasix) and ethacrynic acid (Edecrin)
Some medications can also cause tinnitus (ringing in the ears). These include:
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Certain antidepressants, including amitriptyline and sertraline
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Certain anti-anxiety medications, such as alprazolam (Xanax)
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Certain blood pressure medications, including captopril and propranolol
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Certain cancer medications, including vincristine and vinblastine
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Certain cholesterol-lowering medications, including atorvastatin (Lipitor) and simvastatin (Zocor)
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Certain medications used to treat erectile dysfunction, including sildenafil (Viagra) and tadalafil (Cialis)